多功能玻璃反应釜和中试工厂反应装置

chemReactor CR,15 升 制药反应釜,中试工厂反应装置 chemReactor CR,15 升 制药反应釜,中试工厂反应装置

多功能玻璃反应釜和中试工厂反应装置

 

玻璃-玻璃衬里钢反应器:15、 30、 60、 100、 160、 250 liter
工作压力 -1.0 (FV) - +0.5 bar
工作温度:-60 ° C (-90 ° C) -  + 200 ° C 
材料硼硅酸盐玻璃 3.3,搪玻璃、 聚四氟乙烯、 PFA、 钽

可提供 "无尘室 "安装和其他材料,以满足你的过程的具体要求。


典型应用

  • 化学合成
  • 萃取/蒸发
  • 纯化/结晶
  • 分离
  • 原料药制造
  • 多肽生产
  • 工艺开发
  • 扩大规模
  • 低温反应
  • 小规模生产
  • 中试车间/公斤级实验室

Are you looking for more than standard products?

We develop customized solutions precisely aligned with your processes and requirements.

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关于 chemReactor CR

Buchi 玻璃反应系统在防爆设计上的关键问题有着高性能和可靠性。惰性材料可以保障在完全真空条件下密封的玻璃反应体系中的溶剂和酸以及种类繁多的惰性气体的处理的安全。同样的设备配置可以安全地执行多种化学反应步骤。


该系统包括 :反应釜体为坚固的搪玻璃材料,可提供优良的传热,稳定的工艺条件和温度,其中玻璃部分可通过目测来监控化学反应。蒸馏玻璃部分由 buchiflex 组件 (独特灵活球-套连接关节) 组织架构,构建可靠的完全真空条件过程。

CR 类型 chemReactor 是化工过程开发、 规模发展、 过程模拟和 cGMP 公斤生产批量和半间歇式操作的多功能试验反应器系统。

我们提供化学加工的完整解决方案: 反应器系统包括像取样装置、 ph 值探头、精馏填料及配件、 过程监测和控制以及辅助设备,如温度控制单元,nutsch过滤器 / 干燥机、 洗涤器或混合槽。

 

标准包装配置 / 标准选项

标准包装

  • 全玻璃夹套/玻璃衬里钢反应器
  • 多用途玻璃蒸馏系统上部
  • 不锈钢框架,支持灵活的玻璃上部
  • ATEX Zone 1 (0) / CE / cGMP
  • CIP 能力
  • 符合FDA ,高度耐腐蚀
  • 完整的文档

标准选项

  • 反应釜升降器 (容器清洁)
  • 取样装置
  • pH 监测和控制
  • 气体引入管 (氮气吹扫和活跃气)
  • 真空 / 排气管道
  • 增加加料瓶 / 接收瓶
  • 固体加料器
  • 超低温容器可用于超低温化学反应 (-90 ° C)
  • 特种搪玻璃衬里或 C22 哈氏合金
  • 可对接压力反应器和真空精馏系统
  • IQ / OQ / PQ

Detail view

Reactor vessel
Vessel of a chemRactor CR

Reactor vessel

  • Jacketed glass-lined steel vessel with glass section
  • 15, 30, 60, 100, 160, 250 liter
  • Glass-lined steel impeller stirrer
  • Glass-lined steel baffle
  • Dead-volume free drain valve
chemReactor agitator

ATEX stirrer drive

  • ATEX motor and adjustable transmission
  • ATEX dry running mechanical seal
  • Glass-lined impeller stirrer
Vessel of a chemReactor

Glass dome / Glass lined cover plate

  • Glass cover dome (15, 30 liter)
  • Glass-lined steel cover (60, 100, 160, 250 liter)
  • Fast-action closure for addition of solids
  • 8 connection nozzles
     
chemReactor lift

Lifting / lowering device (optional)

  • Lifting / lowering device
  • Easy opening / closing of the reactor vessel
  • Easy access for cleaning

Distillation glass overhead

All Buchi chemReactors (15 - 250 liter) are available with vertical
condensers and in the compact K-design:

  • Unique flexible ball-socket joints
  • Feed vessel for liquid addition
  • Distillation column / vapor duct with pressure gauge and bursting disc
  • Spiral condenser with vacuum / exhaust connection
  • Vertical condensers or horizontal setup (compact design)
  • Receiver vessel for collection of distillate
  • Dean-Stark phase separator
  • Vacuum / pressure equalization and distribution piping
  • Self-draining «buchiflex» glass piping
Vessel of a chemRactor CR

Reactor vessel

  • Jacketed glass-lined steel vessel with glass section
  • 15, 30, 60, 100, 160, 250 liter
  • Glass-lined steel impeller stirrer
  • Glass-lined steel baffle
  • Dead-volume free drain valve
chemReactor agitator

ATEX stirrer drive

  • ATEX motor and adjustable transmission
  • ATEX dry running mechanical seal
  • Glass-lined impeller stirrer
Vessel of a chemReactor

Glass dome / Glass lined cover plate

  • Glass cover dome (15, 30 liter)
  • Glass-lined steel cover (60, 100, 160, 250 liter)
  • Fast-action closure for addition of solids
  • 8 connection nozzles
     
chemReactor lift

Lifting / lowering device (optional)

  • Lifting / lowering device
  • Easy opening / closing of the reactor vessel
  • Easy access for cleaning

Distillation glass overhead

All Buchi chemReactors (15 - 250 liter) are available with vertical
condensers and in the compact K-design:

  • Unique flexible ball-socket joints
  • Feed vessel for liquid addition
  • Distillation column / vapor duct with pressure gauge and bursting disc
  • Spiral condenser with vacuum / exhaust connection
  • Vertical condensers or horizontal setup (compact design)
  • Receiver vessel for collection of distillate
  • Dean-Stark phase separator
  • Vacuum / pressure equalization and distribution piping
  • Self-draining «buchiflex» glass piping

案例

Videos

Flexible glass connection buchiflex - Glass reactor systems

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