miniPilot® - miniplant pilot reactor

Multipurpose glass reactor for small volumes

Glass reactor: 5, 10, 15 liter
Pressure: -1.0 (FV) to +1.0 bar
Temperature: -60 °C (optional -90 °C) to +200 °C
Material: Borosilicate glass 3.3, PTFE, PFA, PEEK

A clean-room setup and other materials are available to meet your specific process requirements. 

With the miniPilot® product family (reactor, nutsche filter, scrubber) we offer miniplant pilot reactors for chemical process development, scale-up, process simulation and kilo-scale production.

The reactors' explosion proof design (ATEX) and inert materials allow safe processing of solvents and acids in a completely sealed reaction vessel. The compact standard reactor setup can easily be modified, interchangeable reaction vessels of 5, 10 and 15 liter including interchangeable stirrers are available.

The reaction vessel is installed on a lifting / lowering device to simplify opening and cleaning. The distillation glass overhead is built with flexible ball-socket joints for multiple chemical reactions under full vacuum.

We produce complete solutions for chemical processing: Reactor systems including accessories like sampling devices, pH probes, rectification columns with structured packing, process monitoring and control as well as integration of auxiliary equipment such as temperature control units, nutsche filters / dryers, gas scrubbers or mixing vessels.

Package / Options

Standard package

  • Interchangeable 5, 10 and 15 liter jacketed glass reactor
  • Baffle with Pt100 temperature sensor
  • Continuous adjustable agitator speed, 0-600 rpm
  • Dry running mechanical seal
  • Compact stainless steel frame, table or floor model, mobile
  • ATEX Classification: 2G IIB
  • CE, cGMP, TA-Luft
  • CIP capable
  • FDA conform, highly corrosion resistant materials: Glass, PTFE, PFA, PEEK
  • Delivery fully assembled
  • Complete documentation

Standard options

  • Reactor lift for easy reactor opening, cleaning, stirrer exchange
  • 3-wall reactor vessel for -90 °C chemistry
  • Glass distillation overhead
  • Sampling system
  • Probes for pH, others
  • CiP spray nozzle
  • IQ, OQ, PQ

Distillation glass overhead

Optional distillation overhead consisting of:

  • 1 liter feed vessel
  • Vapor duct with reflux splitter
  • Spiral reflux condenser
  • Phase separator
  • 4 liter receiver vessel
  • Distributor with pressure gauge and vacuum connection
  • Nitrogen connection
  • Self-draining «buchiflex» glass piping

Compact, mobile frame

  • Compact stainless-steel frame fits in standard laboratory fume hood
  • Bench-top model
  • Floor model, mobile
  • Vessel lift for easy handling of glass reaction vessels

Solid cover plate

  • PFA coated steel cover plate, 7 ports
  • Fast-action closure for addition of solids
  • Standard version with 4 NS tapered joint
  • 2 spare connections for common laboratory glassware

Stirrer drive, stirrers


Typical applications

  • Chemical synthesis  
  • Extraction / evaporation  
  • Purification / crystallization  
  • Separation
  • cGMP API production
  • Peptide synthesis
  • Process development
  • Scale-up 
  • Cryogenic reactions 
  • Pilot plant / kilo lab