midiPilot® - glass reactor for small volumes

Multipurpose glass reactor for small volumes

Glass reactor: 20 to 30 liter
Pressure: -1.0 (FV) to +0.5 bar
Temperature: -60 °C (optional -90 °C) to +200 °C
Material: Borosilicate glass 3.3, PTFE, PFA, PEEK

A clean-room setup and other materials are available to meet your specific process requirements. 

The midiPilot is our sturdy multipurpose glass reactor for small volumes. It is specifically designed for applications in kilo lab, for chemical process development and cGMP compliant API syntheses.

The reactors' explosion proof design (ATEX) and inert materials allow safe processing of solvents and acids in a completely sealed reaction vessel.

The compact reactor system can easily be modified:  interchangeable reaction vessels of 20 and 30 liter including interchangeable stirrers are available. The glass reactor is equipped with a lifting / lowering device for easy and efficient opening and cleaning.

We produce complete solutions for chemical processing: Reactor systems including accessories like sampling devices, pH probes, rectification columns with structured packing, process monitoring and control as well as integration of auxiliary equipment such as temperature control units, nutsche filters / dryers, gas scrubbers or mixing vessels.

Package / Options

Standard package

  • 20, 30 liter jacketed glass reactor, interchangeable
  • Baffle with Pt100 temperature sensor
  • Continuous adjustable agitator speed, 0-600 rpm
  • Dry running mechanical seal
  • Compact stainless steel frame, table or floor model, mobile
  • ATEX Zone 1 (0), CE, cGMP
  • CIP capable
  • FDA conform, highly corrosion resistant
  • Complete documentation

Standard options

  • Reactor lift for easy reactor opening, cleaning, stirrer exchange
  • 3-wall reactor vessel for -90 °C chemistry
  • Glass distillation overhead
  • Sampling system
  • Probes for pH, others
  • CiP spray nozzle
  • IQ, OQ, PQ

Compact, mobile frame

  • Compact stainless steel frame fits in standard laboratory fume hood
  • Bench-top model
  • Floor model, mobile
  • Vessel lift for easy handling of glass reaction vessels

Distillation glass overhead

Optional distillation overhead consisting of:

  • 10 liter feed vessel
  • Vapor duct with reflux splitter
  • Spiral reflux condenser
  • Phase separator
  • 10 liter receiver vessel
  • Distributor with pressure gauge and vacuum connection
  • Nitrogen connection
  • Self-draining «buchiflex» glass piping

Solid cover plate

  • PFA coated steel cover plate
  • Fast-action closure for addition of solids
  • Standard version with 4 NS tapered joint
  • 2 spare connections for common laboratory glassware


Stirrer drive, stirrers

midiPilot® setups

Typical applications

  • Chemical synthesis  
  • Extraction / evaporation  
  • Purification / crystallization  
  • Separation  
  • API synthesis   
  • Peptide synthesis 
  • Process development 
  • Scale-up 
  • Cryogenic reactions  
  • Small scale production 
  • Pilot plant / kilo lab 






midiPilot® - glass reactor for small volumes

buchiflex - unique glass joint