Stirred nutsche filters (SPPS)

Reactors for solid-phase peptide synthesis (SPPS)

Filtration vessel: 10 - 300 liter
Pressure: -1.0 (FV) to +0.5 bar
Temperature: -60 °C to +200 °C
Filter cloth: Mesh size 8 to 115 micron
Material: Borosilicate glass 3.3, PTFE, PFA, ETFE, glass-lined steel

For other characteristics, see nutsche filters

For decades Buchi has been at the forefront of building pilot and production scale reactors for solid-phase peptide synthesis (SPPS). Our systems are custom designed and made according to your requirements. We offer fully integrated solutions with all auxiliary equipment and automation according to your specifi-cations (incl. recipe control). Our SPPS reactor systems are specifically optimized for cGMP API manufacturing and fulfill all regulatory requirements for safe operations incl. ATEX. 

Stirred nutsche filters are used for filtration as well as for solid phase peptide synthesis (SPPS). Solid phase reactors can be equipped for fully automated processes. 

Stirrers are provided in glass-lined steel, Hastelloy® or stainless steel. The stirrer height can be adjusted pneumatically under full vacuum operation condition, enabling squeezing of the slurry. For more technical features and read the main advantages of our Solid Phase Peptide Synthesis Equipment (SPPS) read here


Typical applications

  • Peptide synthesis 
  • Solid phase peptide synthesis (SPPS) 
  • Filtration / Separation  
  • Drying 
  • Purification 
  • Crystallization 
  • Ion exchange 
  • Chromatography Cannabis extraction (solvent extraction) Cannabinoid extraction 
  • Cannabis extract purification 
  • Cannabis winterization (cannabis extract winterization)